Brain fog in perimenopause

Infographic showing potential benefits of pharmaceutical-grade methylene blue, including cognitive function, mental clarity, cellular energy, and mitochondrial support.

The Nurses’s RX no. 6: Blue pee? Let’s talk 💙

Published on April 7, 2026April 1, 2026 by J. Nicole, RNLeave a comment

Yes, I said blue pee.

Yep, we’re talking about methylene blue today.

One of the first things people notice is that it can turn your urine blue or blue-green. But don’t panic, it’s not dangerous. It’s actually a sign your body is processing it the way it should. Your body uses what it needs and gets rid of the rest.

Nowww… if your 💩 turns blue?

Different conversation. That’s when you reach out to your provider. That plot twist may mean that methylene blue isn’t being broken down in your body the way we want it to.

Methylene blue itself isn’t new at all. It’s a pharmaceutical-grade compounded dye that’s been used in medicine for over 150 years. Hospitals were using it long before wellness trends were even a thing. The version we offer is prescribed and overseen by licensed medical providers, not something pulled from a supplement aisle or online marketplace.

She’s the OG. Truly.

What’s new is the interest in how low doses of methylene blue may support focus, mental clarity, and steadier energy. Especially during seasons like perimenopause, when energy doesn’t feel predictable anymore and brain fog shows up uninvited.

This isn’t a stimulant.

Think less caffeine spike and more steady support. Like a slow, continuous IV infusion instead of a quick IV bolus.
No jitters. No crash.

A lot of the conversation around methylene blue centers on cellular energy, which is really just how efficiently your cells turn oxygen and nutrients into usable energy. When that process slows down, it doesn’t always feel like sleepiness. It often shows up as true mental fatigue, low motivation, or that mid-day crash coffee can’t fix.

There are studies that have suggested methylene blue may play a role in long term brain health and cognitive function, which is why it’s entered the Alzheimer’s conversation. One thing that doesn’t get talked about much is that long-term studies with methylene blue are hard to keep truly “blind.” When something can turn your urine blue, participants and researchers can usually tell who’s taking it, which makes long-term data harder to interpret.

That’s part of why methylene blue keeps getting studied… and also why the conversation around it stays nuanced.

Did I mention our version is a pill, not an injection??? Yep.

So if you’ve wanted to support your energy, focus, and brain health, but didn’t want injections at all… or don’t want to add yet another injection to your stack… you may loooove this little blue pill.

More to come on this one, because the questions around it keep rolling in.

And just to be clear, this is pharmaceutical-grade methylene blue, prescribed based on individual needs, not a grey-market supplement.

XOXO,
NIKI, RN

PCOS. Perimenopause. Metabolic health. The real stuff. Not just “eat less, move more.”

ask me anything

trusted wellness tools

Not sure where to start? Take my free quiz and I’ll send you a custom plan.
WHAT’S RIGHT FOR MY BODY?
P.S. Missed the previous editions of The Nurse’s RX?
↓ Catch up here ↓
READ PAST EDITIONS

↓ LET’S CONNECT ↓

_{Let’s be clear about who I am (and who I’m not)}

_{I’m a registered nurse and health coach who shares real, BS-free information about metabolic health, PCOS, perimenopause, and weight loss, because y’all deserve better than vague wellness fluff. But here’s what I need you to know: I am not YOUR nurse. Everything I share here is for educational purposes only. It is not medical advice, it’s not a diagnosis, and it doesn’t create a provider-patient relationship between us. Nothing here replaces the care of a licensed provider who actually knows your full health history. The opinions and content here are my own and do not reflect the views of my employer or the hospital where I work.}

_{Scope of practice}

_{As a nurse health coach, I can recommend over-the-counter products and supplements that may support your wellness goals. I don’t prescribe specific prescription medications. When it comes to GLP-1s and peptides, what I can do is talk about the science, what’s available, and what may be beneficial, so you can have an informed conversation with your licensed medical provider. The decision about what’s right for your body always belongs to you and your provider. Always consult your licensed provider before starting any prescription treatment. These statements have not been evaluated by the FDA. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.}

_Transparency

_{I only recommend things I actually trust. Most are products I personally use, some are from partners whose clinical standards I believe in. I will always let you know when it’s something I haven’t tried personally. Some links in this email are affiliate links or part of brand partnerships, which means I may earn a commission at no extra cost to you. As an Amazon Associate, I earn from qualifying purchases.}

_{Results + Testimonials}

_{Any testimonials or results shared here reflect individual experiences only. Results are not guaranteed and will vary based on individual circumstances.}

_{Read the full fine print at nicoleinscrubs.com/disclosure}

Ellie MD NAD+ benefits infographic showing a vial surrounded by health benefits like energy, weight loss, anti-aging, and cognitive enhancement.

The Nurse’s RX no. 1: When caffeine just isn’t cutting it anymore

Published on March 18, 2026March 31, 2026 by J. Nicole, RNLeave a comment

Hey Hey!

You ever hit that point where coffee feels like emotional support at this stage, but the energy part packed up and left? Same.

That’s when I learned about NAD+. It’s basically the MVP molecule that helps your body turn food into actual, usable energy. Think of it like the little spark plug inside your cells that keeps everything running — focus, metabolism, mood, all of it.

But here’s the kicker. NAD+ levels drop as we age, stress, or live on caffeine and vibes (guilty). Supporting those levels can help your body’s natural energy process stay on track. For me, it’s been the difference between dragging and doing.

Not a miracle fix, just a subtle, steady kind of clarity that coffee wishes it could give.

If you want the nerdy breakdown of how NAD+ works or what it’s like to start, comment below and I’ll send you my quick NAD+ 101 note.

BOOK A FREE CALL WITH ME

TRUSTED WELNESS TOOLS

TEXT ME YOUR QUESTIONS

↓ LET’S CONNECT ↓

_{Professional Disclosure: I provide BS-free metabolic education as a registered nurse and health coach for women navigating PCOS, perimenopause, and stubborn weight loss. While I share evidence-based research and nurse-informed support, please remember that I am not your nurse. The content shared here is for educational purposes only. It does not constitute medical advice, diagnosis, or treatment, and it does not establish a provider-patient relationship. Nothing on this site is a substitute for care from a licensed provider who knows your full health history. All opinions and content shared on this platform are my own and do not reflect the views or endorsements of my employer or the hospital where I am employed.}

_{Scope of Practice and FDA: Per professional coaching guidelines, I may recommend over the counter (OTC) medications or supplements to support your wellness goals. However, I do not prescribe or recommend specific prescription medications. For prescription options, including GLP-1 tools, my role is to help you understand the available science so you can have an informed discussion with your licensed healthcare provider. These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease, and medical treatments require professional oversight.}

_{Trust and Transparency: I only recommend products I trust. Most are items I use personally, while others are shared based on my professional trust in the clinical standards of partners like Ellie MD. Some links are affiliate links or part of brand partnerships, which means I may earn a commission at no extra cost to you. As an Amazon Associate I earn from qualifying purchases.}

Why is my pee blue? The “OG” Secret for Brain Fog and Energy

Published on March 14, 2026March 27, 2026 by J. Nicole, RNLeave a comment

Let’s be real for a second. If you looked down and saw blue or blue-green pee in the toilet, you’d probably freak out just a little, right? But what if I told you that “blue pee” is actually the latest buzz in the wellness world for kicking brain fog to the curb?

We’re talking about Methylene Blue.

If you’ve been feeling like your brain is stuck in a permanent mid-afternoon slump, or if perimenopause has invited “brain fog” to live in your head rent-free, you’re going to want to read this.

What is Methylene Blue? (And no, it’s not a TikTok trend)

While it might be trending on social media, Methylene Blue is actually the “OG” of medicine. It’s a pharmaceutical-grade compounded dye that has been used by doctors and hospitals for over 150 years.

Unlike those random supplements you find in a late-night scrolling session on an online marketplace, the version I’m obsessed with is prescribed and overseen by licensed medical providers through EllieMD.

The “Blue Pee” Mystery Solved

First things first: the blue pee. It’s totally normal! It’s just a sign that your body is processing the Methylene Blue exactly how it should. Your system takes what it needs for cellular energy and flushes out the rest.

Pro-Tip: If your 💩 turns blue, that’s a different story. That’s a “call your provider” moment because it means your body isn’t breaking it down quite right.

Why Women are Reaching for Methylene Blue for Brain Fog

If you are in the perimenopause trenches, you know that energy isn’t exactly predictable anymore. One minute you’re fine, the next you’re hitting a wall that even an Alani can’t fix.

Methylene Blue is being studied for its potential to support:

Mental Clarity: Helping you find your keys (and your train of thought).
Physical Energy: Boosting how your cells turn oxygen into fuel.
Cognitive Function: Supporting long-term brain health and memory.

Steady Support, Not a Caffeine Crash

The best part? This isn’t a stimulant. You won’t get those shaky, “I had too much espresso” jitters. Think of it less like a quick caffeine spike and more like a slow, steady stream of support for your cells.

It’s all about mitochondrial health. When your “cellular batteries” are running low, it doesn’t just feel like you’re tired. It feels like a total lack of motivation and true mental fatigue.

Why the “Pill” Version is a Game Changer

I know a lot of us in the wellness space are used to injections, but let’s be honest: sometimes we just want things to be simple.

If you’ve been looking for ways to increase energy without more shots, you are going to love this. Our version is a simple pill. No needles, no fuss, just pharmaceutical-grade support tailored to your individual needs.

Is Methylene Blue Right for You?

There is so much nuance to this conversation, especially since it’s even being studied in relation to Alzheimer’s and long-term cognitive care. Because it’s so unique (and because it turns your pee blue!), it’s hard for scientists to do “blind” studies, which is why it stays such a hot topic for research.

If you’re ready to stop guessing and start supporting your brain health with something backed by science, let’s chat about adding this to your routine.

IS METHYLENE BLUE RIGHT FOR ME?

CLICK HERE TO BOOK A FREE 15 MIN CALL WITH ME

OR YOU CAN JUST TEXT ME YOUR QUESTIONS