mental clarity

The Nurses’s RX no. 6: Blue pee? Let’s talk 💙

Published on April 7, 2026April 1, 2026 by J. Nicole, RNLeave a comment

Yes, I said blue pee.

Yep, we’re talking about methylene blue today.

One of the first things people notice is that it can turn your urine blue or blue-green. But don’t panic, it’s not dangerous. It’s actually a sign your body is processing it the way it should. Your body uses what it needs and gets rid of the rest.

Nowww… if your 💩 turns blue?

Different conversation. That’s when you reach out to your provider. That plot twist may mean that methylene blue isn’t being broken down in your body the way we want it to.

Methylene blue itself isn’t new at all. It’s a pharmaceutical-grade compounded dye that’s been used in medicine for over 150 years. Hospitals were using it long before wellness trends were even a thing. The version we offer is prescribed and overseen by licensed medical providers, not something pulled from a supplement aisle or online marketplace.

She’s the OG. Truly.

What’s new is the interest in how low doses of methylene blue may support focus, mental clarity, and steadier energy. Especially during seasons like perimenopause, when energy doesn’t feel predictable anymore and brain fog shows up uninvited.

This isn’t a stimulant.

Think less caffeine spike and more steady support. Like a slow, continuous IV infusion instead of a quick IV bolus.
No jitters. No crash.

A lot of the conversation around methylene blue centers on cellular energy, which is really just how efficiently your cells turn oxygen and nutrients into usable energy. When that process slows down, it doesn’t always feel like sleepiness. It often shows up as true mental fatigue, low motivation, or that mid-day crash coffee can’t fix.

There are studies that have suggested methylene blue may play a role in long term brain health and cognitive function, which is why it’s entered the Alzheimer’s conversation. One thing that doesn’t get talked about much is that long-term studies with methylene blue are hard to keep truly “blind.” When something can turn your urine blue, participants and researchers can usually tell who’s taking it, which makes long-term data harder to interpret.

That’s part of why methylene blue keeps getting studied… and also why the conversation around it stays nuanced.

Did I mention our version is a pill, not an injection??? Yep.

So if you’ve wanted to support your energy, focus, and brain health, but didn’t want injections at all… or don’t want to add yet another injection to your stack… you may loooove this little blue pill.

More to come on this one, because the questions around it keep rolling in.

And just to be clear, this is pharmaceutical-grade methylene blue, prescribed based on individual needs, not a grey-market supplement.

XOXO,
NIKI, RN

PCOS. Perimenopause. Metabolic health. The real stuff. Not just “eat less, move more.”

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_{Let’s be clear about who I am (and who I’m not)}

_{I’m a registered nurse and health coach who shares real, BS-free information about metabolic health, PCOS, perimenopause, and weight loss, because y’all deserve better than vague wellness fluff. But here’s what I need you to know: I am not YOUR nurse. Everything I share here is for educational purposes only. It is not medical advice, it’s not a diagnosis, and it doesn’t create a provider-patient relationship between us. Nothing here replaces the care of a licensed provider who actually knows your full health history. The opinions and content here are my own and do not reflect the views of my employer or the hospital where I work.}

_{Scope of practice}

_{As a nurse health coach, I can recommend over-the-counter products and supplements that may support your wellness goals. I don’t prescribe specific prescription medications. When it comes to GLP-1s and peptides, what I can do is talk about the science, what’s available, and what may be beneficial, so you can have an informed conversation with your licensed medical provider. The decision about what’s right for your body always belongs to you and your provider. Always consult your licensed provider before starting any prescription treatment. These statements have not been evaluated by the FDA. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.}

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_{I only recommend things I actually trust. Most are products I personally use, some are from partners whose clinical standards I believe in. I will always let you know when it’s something I haven’t tried personally. Some links in this email are affiliate links or part of brand partnerships, which means I may earn a commission at no extra cost to you. As an Amazon Associate, I earn from qualifying purchases.}

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Ellie MD NAD+ vial bottle on a cozy blanket with a list of benefits: Boosted Energy Levels, Enhanced Cellular Repair, Improved Cognitive Function, Metabolic Support, and Anti-Aging Properties.

NAD+ for Chronic Fatigue: Why Your System is Crashing

Published on December 4, 2025March 27, 2026 by J. Nicole, RNLeave a comment

Tired of Running on Empty? The Cellular Key to Boosting Metabolism & Focus

That Energy Drink Crash is NOT Normal

You ever hit the point where your third Alani just feels like a very expensive can of fizzy disappointment? Were you relying on that quick jolt to get you through your day (or night if you’re like me), but the energy part packed up and left the building? SAME SIS, SAME!

That crashing feeling, that chronic metabolic fatigue, isn’t just about poor habits. The truth is, it might be a shortage of a critical molecule your body needs to function at its peak.

The Spark Plug (NAD+) Inside Every Cell

What is truly running the stage for The Greatest Show (which is you, girl)? It’s a molecule called NAD+ (Nicotinamide Adenine Dinucleotide).

NAD+ is basically the MVP molecule that helps your body turn food into actual, usable energy. Think of NAD+ as the spark plug for your cellular engine. You need a strong spark to ignite your fuel and get moving. The studies show that NAD+ helps keep your cells young and resilient and improves how your body’s Energy Factory works, which is the heart of your energy production. For me, it was like the five thousand tabs in my brain finally closed themselves.

It keeps everything running smoothly:

Focus
Metabolism
Mood

The Spark Plug runs all of it. When the spark plug is weak, every system reading, from your energy output to your focus, is compromised.

The Metabolic Stressors Aging Your Energy

So if NAD+ is so critical for cellular energy, why do we constantly feel so depleted?

NAD+ levels drop as we age. This is unavoidable. But those levels also drop due to chronic stress or when we are running on caffeine and vibes. You are surviving on pure grit, and your brain literally feels like TV static.

In my own experience, this is where I saw the biggest win. That overwhelming, chaotic ADHD haze I used to deal with started easing up; it was like the five thousand tabs stuck open in my brain finally closed themselves instead of crashing. I felt clearer and more “with it.”

The Glow Up is Real (Even the Awkward Part)

NAD+ plays a major role in cellular energy and turnover, which is great for your skin. I can tell you that my skin definitely had its own little purge moment at first—hello, surprise zits! But that initial reaction can be a normal part of the process.

Once that purge was over? Game changer. People were literally giving me compliments and asking what foundation I was wearing because my skin looked so good—and I wasn’t even wearing any! That’s when I knew the NAD+ was doing the dang thing and the cell turnover was happening!

The Difference Between Dragging and Doing

Supporting those NAD+ levels can help your body’s natural energy process stay on track. It’s not a miracle fix or a sudden jittery jolt; it’s a subtle, steady kind of clarity that coffee wishes it could give.

It’s the simple difference between dragging and doing. If you’re tired of guessing and you just want reliable energy, supporting this molecule is the most common sense, science-backed place to put your focus.

Want the Full Scoop on the Cellular Maintenance?

If you’re curious about the next-level science on cellular maintenance and DNA repair benefits of NAD+ that weren’t covered here, I have an exclusive NAD+ 101 note that is just for you!

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P.S. If this post helped you finally understand your energy crash, share it with a friend who is also tired of relying on that third can of Alani!

_{Professional Disclosure: I provide BS-free metabolic education as a registered nurse and health coach for women navigating PCOS, perimenopause, and stubborn weight loss. While I share evidence-based research and nurse-informed support, please remember that I am not your nurse. The content shared here is for educational purposes only. It does not constitute medical advice, diagnosis, or treatment, and it does not establish a provider-patient relationship. Nothing on this site is a substitute for care from a licensed provider who knows your full health history. All opinions and content shared on this platform are my own and do not reflect the views or endorsements of my employer or the hospital where I am employed.}

_{Scope of Practice and FDA: Per professional coaching guidelines, I may recommend over the counter (OTC) medications or supplements to support your wellness goals. However, I do not prescribe or recommend specific prescription medications. For prescription options, including GLP-1 tools, my role is to help you understand the available science so you can have an informed discussion with your licensed healthcare provider. These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease, and medical treatments require professional oversight.}

_{Trust and Transparency: I only recommend products I trust. Most are items I use personally, while others are shared based on my professional trust in the clinical standards of partners like Ellie MD. Some links are affiliate links or part of brand partnerships, which means I may earn a commission at no extra cost to you. As an Amazon Associate I earn from qualifying purchases.}